4-Fluorobenzaldehyde CAS#459-57-4

1.CAS Number: 459-57-4

2.Chemical Formula: C7H5FO

3.Synonyms:

Paroxetine Impurity 58

4-fluoro-benzaldehyd

Benzaldehyde, p-fluoro-

4.Appearance: Clear colorless to yellow Liquid

5.HS Code: 29130000

6.MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

Products Description

4-Fluorobenzaldehyde (CAS No. 459-57-4) serves as a key intermediate for organic synthesis. It is generally a colorless to pale yellow liquid with a distinctive aromatic smell. Possessing typical aldehyde chemical characteristics, it can participate in oxidation, reduction and condensation reactions. The fluorine atom embedded in its molecular structure delivers special reactivity, which enables this compound to act as a unique reactive moiety in diverse synthetic routes.

4-Fluorobenzaldehyde CAS#459-57-4

Products Chemical Properties

Melting point -10 °C (lit.)
Boiling point 181 °C/758 mmHg (lit.)
density 1.157 g/mL at 25 °C (lit.)
vapor pressure 19 hPa (70 °C)
refractive index n20/D 1.521(lit.)
Fp 134 °F
storage temp. Store below +30°C.
solubility Chloroform, Methanol
form Liquid
color Clear colorless to yellow
Specific Gravity1.157
Water Solubility IMMISCIBLE
Sensitive Air Sensitive
BRN 385857
Stability:Air Sensitive
InChIKeyUOQXIWFBQSVDPP-UHFFFAOYSA-N
CAS DataBase Reference459-57-4(CAS DataBase Reference)
NIST Chemistry ReferenceBenzaldehyde, 4-fluoro-(459-57-4)
EPA Substance Registry SystemBenzaldehyde, 4-fluoro- (459-57-4)

 Safety Information

Hazard Codes Xi,F
Risk Statements 36/37/38
Safety Statements 26-36-37/39-36/37/39-27
RIDADR UN 1989 3/PG 3
WGK Germany 2
F 9-23
Hazard Note Flammable
TSCA T
HazardClass 3.2
PackingGroup III
HS Code 29130000

Products Application

As a fluorinated benzaldehyde derivative, 4-Fluorobenzaldehyde demonstrates inhibitory effects on mushroom tyrosinase. It functions as a critical synthetic intermediate, most prominently for manufacturing pyrazolopyridine derivatives, a class of mitogen-activated protein kinase (MAPK) inhibitors. Beyond this, the compound is widely deployed in the synthesis of a broad spectrum of pharmaceutical molecules.

4-Fluorobenzaldehyde CAS#459-57-4
4-Fluorobenzaldehyde CAS#459-57-4

Company Profile

Furuida (Jinan) Chemical Technology Co., Ltd. is more than a chemical supplier; it is a one-stop solutions partner. From its base in Shandong, China, the company integrates R&D, production, sales, and global services, with a focus on new chemical materials. Integrity, quality, and customer-first service define its approach. Continuous innovation and strict quality management drive its international growth, operational standards, and brand reputation.

Its scale is significant: annual sales above RMB 600 million, over 5,000 industrial clients, and markets across Asia, Europe, Africa, and Oceania. An experienced foreign trade and technical support team, a mature global supply network, and resilient supply chain capabilities make this possible.

Furuida’s portfolio includes pharmaceutical intermediates and raw materials, food additives, electroplating chemicals, water treatment agents, dye auxiliaries, functional materials, titanium compounds, metal salts, catalysts, and surfactants. These products serve pharmaceuticals, electronics, coatings, rubber and plastics, fine chemicals, and water treatment. For global partners, Furuida delivers reliable, cost-effective chemical solutions and comprehensive one-stop services.

4-Fluorobenzaldehyde CAS#459-57-4
4-Fluorobenzaldehyde CAS#459-57-4

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