Piroctone Olamine (CAS No. 68890-66-4)
Piroctone olamine (INN), also referred to as piroctone ethanolamine and marketed under the trade name Octopirox, is a compound used in the treatment of fungal infections. It is the ethanolamine salt form of piroctone, a hydroxamic acid derivative.
Piroctone olamine Chemical Properties
| Melting point | 134.0 to 138.0 °C |
| Boiling point | 135-235℃[at 101 325 Pa] |
| density | 1.1[at 20℃] |
| vapor pressure | 0-0Pa at 20-25℃ |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly, Sonicated), Methanol (Slightly) |
| pka | 5.9-7.4[at 20 ℃] |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 400-50000mg/L at 20-25℃ |
| Merck | 147502 |
| Major Application | agriculture |
| environmental | |
| Cosmetics Ingredients Functions | PRESERVATIVE |
| ANTI-SEBORRHEIC | |
| InChI | InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2 |
| InChIKey | BTSZTGGZJQFALU-UHFFFAOYSA-N |
| SMILES | C(N)CO.C(C1=CC(C)=CC(=O)N1O)C(C)CC(C)(C)C |
| LogP | 1.05-3.86 at 20-25℃ |
| CAS DataBase Reference | 68890-66-4(CAS DataBase Reference) |
| WGK Germany | 2 |
| RTECS | UU7786150 |
| HS Code | 2933399090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Aquatic Chronic 3 |
| Eye Dam. 1 | |
| Skin Irrit. 2 |
Product Applications of Piroctone Olamine (CAS No. 68890-66-4)
Piroctone olamine is commonly used in combination with other ingredients in shampoo formulations, where it helps effectively reduce dandruff while also providing conditioning benefits for hair. Recent studies have also indicated that piroctone olamine may induce apoptosis and demonstrate significant in vivo activity against myeloma.
Company Profile
Furuida (Jinan) Chemical Technology Co., Ltd., located in Shandong, China, is a modern fine chemical enterprise integrating R&D, production, sales, and global services. Focused on new chemical materials, the company adheres to the values of integrity, quality, and customer-centric service. Propelled by ongoing innovation and rigorous quality control, it continues to advance its global reach, operational efficiency, and brand development.
The company is supported by a skilled team in foreign trade and technical support, a mature global supply system, and strong supply chain capabilities. With annual sales exceeding RMB 600 million, it serves more than 5,000 industrial customers worldwide. Its business spans many countries and regions across Asia, Europe, Africa, and Oceania, earning it a solid global clientele and a strong reputation in the industry.
Furuida’s core product offerings include pharmaceutical raw materials, food additives, electroplating chemicals, water treatment agents, dye auxiliaries, functional new materials, titanium compounds, metal salts, catalysts, and surfactants. Widely used in pharmaceuticals, electronics, coatings, rubber and plastics, fine chemicals, and water treatment, these products allow the company to consistently deliver stable, cost-effective chemical solutions and comprehensive one-stop services to its global partners.
