Methanesulfonic Acid CAS#75-75-2

1.CAS Number: 75-75-2 

2.Chemical Formula: CH4O3

3.Synonyms: 

Kyselina methansulfonova 

Methylsulphonicacid 

METHANE SULFONIC ACID 70% 

4.Appearance: Colorless liquid 

5.HS Code: 29041000 

6.MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

Products Description

Methanesulfonic acid (CH₃SO₃H, MSA) is a potent organic acid. In the atmosphere, substantial quantities of MSA are generated via chemical oxidation of dimethyl sulfide, and it is biodegradable, breaking down into carbon dioxide and sulfate. Compared with mineral acids, MSA features lower toxicity and reduced corrosiveness, earning it recognition as a green‑grade acid. Its aqueous solution is widely used as a reference electrolyte for electrochemical applications.

Chemically categorized as an alkanesulfonic acid, MSA carries a methyl group directly bonded to the sulfo functional group. It occurs as a metabolite of Escherichia coli, and is classified both as an alkanesulfonic acid and a one‑carbon compound. It is the conjugate acid of methanesulfonate anion.

Methanesulfonic acid CAS#75-75-2

Products Chemical Properties

Melting point 17-19 °C (lit.)
Boiling point 167 °C/10 mmHg (lit.)
density 1.475-1.485 g/mL at 20 °C 1.481 g/mL at 25 °C (lit.)
vapor density 3.3 (vs air)
vapor pressure 1 mm Hg ( 20 °C)
refractive index n20/D 1.429(lit.)
Fp >230 °F
storage temp. 2-8°C
solubility water: soluble1,000 g/L at 20°C
form Solution
pka-2.6(at 25℃)
Specific Gravity1.48 (18/4℃)
color brown
biological sourcesynthetic
Water Solubility Miscible with water. Slightly miscible with benzene and toluene. Immiscible with paraffins.
λmaxλ: 240-320 nm Amax: <0.4
Sensitive Light Sensitive & Hygroscopic
Merck 14,5954
BRN 1446024
Stability:Stable. Moisture sensitive. Incompatible with amines, bases, water, common metals. Releases a substantial amount of heat when diluted with water (add acid to water with care if diluting).
InChIKeyAFVFQIVMOAPDHO-UHFFFAOYSA-N

CAS DataBase 

Reference

75-75-2(CAS DataBase Reference)

NIST Chemistry 

Reference

CH3SO3H(75-75-2)

EPA Substance 

Registry System

Methanesulfonic acid (75-75-2)


Safety Information

Hazard Codes C
Risk Statements 34-22-21/22-35

Safety 

Statements 

26-36-45-1/2-36/37/39
RIDADR UN 3265 8/PG 2
WGK Germany 1
RTECS PB1140000
TSCA Yes
HazardClass 8
PackingGroup III
HS Code 29041000

Hazardous 

Substances Data

75-75-2(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 649 mg/kg LD50 dermal Rabbit 200 - 2000 mg/kg

Products Application

Methanesulfonic acid functions as an acid catalyst for esterification, alkylation and condensation. Its suitability stems from low volatility and favorable solubility in organic media. It contributes to the synthesis of starch esters, oxidized wax esters, benzoic acid esters, phenolic esters and alkyl esters.

It reacts with sodium borohydride in tetrahydrofuran to yield borane‑THF complex. High purity and absence of chloride render it qualified for battery‑system uses. Within the pharmaceutical sector, it supports the production of APIs including telmisartan and eprosartan.

Other uses cover ion chromatography. It supplies carbon and energy for selected gram‑negative methylotrophic bacteria and takes part in peptide deprotection.

Methanesulfonic acid CAS#75-75-2
Methanesulfonic acid CAS#75-75-2

Company Profile

Furuida (Jinan) Chemical Technology Co., Ltd., located in Shandong, China, is a modern fine chemical enterprise that integrates R&D, production, sales, and global services. With a strong focus on new chemical materials, the company upholds the core values of integrity, quality, and customer-centric service. Driven by continuous innovation and rigorous quality control, it is steadily advancing its international presence, operational excellence, and brand development.

The company boasts an experienced team in foreign trade operations and technical support, supported by a mature global supply system and robust supply chain capabilities. With annual sales exceeding RMB 600 million, it serves over 5,000 industrial customers worldwide. Its business activities span numerous countries and regions across Asia, Europe, Africa, and Oceania, having earned the company a solid global clientele and an outstanding reputation within the industry.

Furuida’s product portfolio comprises pharmaceutical raw materials, food additives, electroplating chemicals, water treatment agents, dye auxiliaries, functional new materials, titanium compounds, metal salts, catalysts, and surfactants. Widely utilized in pharmaceuticals, electronics, coatings, rubber and plastics, fine chemicals, and water treatment, these products enable the company to consistently deliver stable, cost-effective chemical solutions and comprehensive, one-stop services to its global partners.

Methanesulfonic Acid
Methanesulfonic Acid

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