Products Description
Trifluoromethanesulfonic acid, widely known under common names including triflic acid, TFMS, TFSA, HOTf and TfOH, is a sulfonic‑acid compound with molecular formula CF₃SO₃H. Classified as one of the well‑known superacids, it ranks among the strongest acids available.
It finds broad‑ranging uses in pharmaceutical manufacturing, agrochemicals and polymer production, and its acid form is extensively deployed for fine‑chemical synthesis. Benefiting from its non‑oxidizing character, high thermal stability and resistance to both oxidation and reduction reactions, it represents one of the most practically valuable members within the superacid family. Within pharmaceutical manufacturing, it supports the synthesis of multiple drug categories such as nucleosides, antibiotics, steroids, proteins and glycosides. As a related derivative, triflic anhydride readily undergoes hydrolysis upon contact with water and carries unfavorable toxicological properties.
Products Chemical Properties
| Melting point | -40 °C |
| Boiling point | 162 °C (lit.) |
| density | 1.696 g/mL at 25 °C (lit.) |
| vapor density | 5.2 (vs air) |
| vapor pressure | 8 mm Hg ( 25 °C) |
| refractive index | n20/D 1.327(lit.) |
| RTECS | PB2771000 |
| Fp | None |
| storage temp. | Store below +30°C. |
| solubility | Miscible in H<sub>2</sub>O |
| pka | -14(at 25℃) |
| form | Fuming Liquid |
| color | slightly brown |
| Specific Gravity | 1.696 |
| PH | <1 (H2O) |
| Water Solubility | SOLUBLE |
| Sensitive | Hygroscopic |
| Merck | 14,9676 |
| BRN | 1812100 |
| Stability: | Stable. Incompatible with acids, alkalis, metals. |
| InChIKey | ITMCEJHCFYSIIV-UHFFFAOYSA-N |
| LogP | 0.3 at 25℃ |
| CAS DataBase Reference | 1493-13-6(CAS DataBase Reference) |
| NIST Chemistry Reference | CF3SO3H(1493-13-6) |
| EPA Substance Registry System | Methanesulfonic acid, trifluoro- (1493-13-6) |
Safety Information
| Hazard Codes | C |
| Risk Statements | 21/22-35-10 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 3265 8/PG 2 |
| WGK Germany | 2 |
| F | 3-10 |
| Hazard Note | Corrosive/Hygroscopic |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29049020 |
| Toxicity | LD50 orally in Rabbit: 1605 mg/kg LD50 dermal Rat > 2000 mg/kg |
Products Application
Trifluoromethanesulfonic acid fulfills a variety of functional roles. It acts as a catalyst for Friedel‑Crafts‑type reactions including acylation, alkylation and polymerization, serves as a solvent for electron spin resonance (ESR) measurements, and functions as a non‑aqueous strong‑acid titrant. Combined with trifluoroacetic acid, it finds application in solid‑phase peptide synthesis. Furthermore, it is acknowledged as one of the most potent monoprotic acids.
Company Profile
Headquartered in Shandong, China, Furuida (Jinan) Chemical Technology Co., Ltd. is a sophisticated fine chemical enterprise integrating independent research and development, standardized production, global sales and all-round international services. Centered on the R&D and industrialization of new chemical materials, the company adheres to the business philosophy of integrity-based operation, quality prioritization and customer-first service. Sustained technological innovation and stringent standardized quality management underpin our steady global expansion, continuous operational optimization and consistent brand value enhancement in the international marketplace.
Backed by an experienced professional team specializing in international trade and technical after-sales support, a well-established global distribution network and strong integrated supply chain capabilities, the company delivers outstanding market performance with an annual sales turnover of over RMB 600 million. We serve more than 5,000 industrial clients worldwide, covering major markets across Asia, Europe, Africa and Oceania. Long-term reliable product quality and professional services have earned us high industry credibility and a stable, loyal global customer base.
Our diversified core product portfolio consists of pharmaceutical raw materials and intermediates, food additives, electroplating chemicals, water treatment agents, dye auxiliaries, functional advanced new materials, titanium compounds, metal salts, catalysts and surfactants. These high-performance chemical products are extensively deployed in pharmaceuticals, electronics, coatings, rubber and plastics, fine chemical manufacturing and water treatment industries. Dedicated to creating maximum value for global partners, Furuida provides worldwide clients with consistently stable, premium-grade chemical products and integrated customized one-stop service solutions.
