Products Description
Omeprazole (CAS 73590‑58‑6) belongs to the class of proton pump inhibitors (PPIs) and is clinically used to treat peptic ulcers and gastroesophageal reflux disease (GERD). Acting on proton pumps within gastric parietal cells, omeprazole transforms into its bio‑active sulfenamide derivative. It then forms irreversible disulfide linkages with sulfhydryl groups of H⁺‑K⁺‑ATPase (the gastric proton pump), yielding a stable sulfenamide‑proton pump complex. This covalent binding deactivates the enzyme, halting hydrogen ion transport from parietal cells into the gastric cavity and interrupting the final stage of gastric acid production, which substantially lowers gastric acid concentration. Accordingly, omeprazole delivers powerful, long‑term suppression of gastric acid secretion provoked by diverse stimuli. It suppresses both basal acid output and acid release stimulated by histamine, pentagastrin and vagal excitation. Notably, it also inhibits acid secretion driven by dibutyryl cyclic adenosine monophosphate, a pathway unresponsive to H₂‑receptor antagonists. Such robust and prolonged pharmacological effect stems from its irreversible inhibition against the proton pump; gastric acid secretion resumes only after the human body synthesizes new proton‑pump proteins.
Products Chemical Properties
| Melting point | 156°C |
| Boiling point | 600.0±60.0 °C(Predicted) |
| density | 1.332 g/cm3 |
| Fp | 9℃ |
| storage temp. | 2-8°C |
| solubility | H2O: 0.5 mg/mL |
| form | solid |
| pka | pKa 4.14/8.9(H2O,t =25,I=0.025) (Uncertain) |
| color | white |
| Water Solubility | Soluble in water (0.5 mg/ml), DMSO (25 mg/ml), and ethanol (4.5 mg/ml). |
| Merck | 146845 |
| BCS Class | 2 |
| Stability: | Stable, but hygroscopic and photosensitive. Incompatible with strong oxidizing agents. Store in the dark. |
| InChIKey | SUBDBMMJDZJVOS-UHFFFAOYSA-N |
| CAS DataBase Reference | 73590-58-6(CAS DataBase Reference) |
| EPA Substance Registry System | 1H-Benzimidazole, 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]- (73590-58-6) |
Safety Information | |
| Hazard Codes | Xi,T,F |
| Risk Statements | 36/37/38-39/23/24/25-23/24/25-11 |
| Safety Statements | 26-36-37/39-45-36/37-16-7 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 2 |
| RTECS | DD9087000 |
| HS Code | 29333990 |
| Hazardous Substances Data | 73590-58-6(Hazardous Substances Data) |
| Toxicity | LD50 in mice, rats (g/kg): 0.08, >0.05 i.v.; >4, >4 orally (Ekman) |
Products Application
Omeprazole is clinically indicated for gastric ulcers, duodenal ulcers, stress‑related ulcers and other comparable gastrointestinal disorders. It is also applied for reflux esophagitis and gastrinoma management.
For injection‑grade omeprazole, additional clinical scenarios cover multiple use cases. It treats gastrointestinal bleeding originating from peptic ulcers or anastomotic ulcers, and prevents upper gastrointestinal bleeding triggered by critical conditions such as cerebral hemorrhage, severe trauma and gastric surgery. It addresses acute gastric mucosal injury induced by stress or non‑steroidal anti‑inflammatory drugs. Besides, it is used to guard against gastric acid reflux and aspiration pneumonia among patients under general anesthesia, post‑major‑surgery subjects and comatose patients.
When administered in combination with amoxicillin plus clarithromycin, or metronidazole plus clarithromycin, omeprazole achieves effective eradication of Helicobacter pylori (H. pylori).
Company Profile
Shandong Furuida Chemical Co., Ltd. delivers reliable chemical raw material supply through a fully integrated factory-direct model—from production and quality control to global trade and logistics.
The company is a global start-up chemical foreign trade enterprise, strategically located in Shandong Province's core chemical industrial zone. Self-owned standardized factories form the foundation of its operations, enabling seamless integration across manufacturing, quality assurance, cross-border trade, and international logistics. This integrated approach ensures independent production capacity and effective market development worldwide.
The company supplies basic chemical raw materials, fine intermediates, chemical additives, and rubber/plastic feedstocks to industries including rubber and plastics, coatings, daily chemicals, building materials, and textiles. Customized formulations and one-stop foreign trade services—covering customs clearance, logistics, and after-sales technical support—are available to meet diverse client needs.
By adopting a factory-direct supply model, the company eliminates intermediary markups and offers transparent, stable pricing. A full-process quality management system guarantees product consistency, while mature cross-border logistics capabilities shorten delivery cycles and enhance supply chain reliability.
With market coverage across Asia, Europe, the Americas, and the Middle East, the company serves chemical manufacturers, terminal processing plants, and cross-border traders with high-quality, cost-effective raw materials and professional service.
