Products Description
Ceftriaxone belongs to the third‑generation broad‑spectrum cephalosporin class of antibiotics. It exerts antibacterial effects by interfering with the biosynthesis of the peptidoglycan layer, thereby suppressing bacterial cell‑wall assembly. Both in‑vitro and in‑vivo research demonstrate that the compound can up‑regulate the expression of excitatory amino acid transporter‑2 within the central nervous system and alleviate glutamatergic‑mediated toxicity.
Products Chemical Properties
| Melting point | 236 °C |
| alpha | D25 -165° (c = 1 in water) (calc for water-free substance) |
| refractive index | -160 ° (C=1, H2O) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | H2O: soluble50mg/mL |
| pka | ~3 (COOH), 3.2 (NH3+), 4.1 (enolic OH) |
| form | powder or crystals |
| color | White to Off-White |
| Water Solubility | Freely soluble in water |
| InChIKey | FDRNWTJTHBSPMW-BBJOQENWSA-L |
Safety Information | |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-42/43 |
| Safety Statements | 26-36-45-37-24-22 |
| WGK Germany | 1 |
| RTECS | XI0368800 |
| HS Code | 29349990 |
| Toxicity | LD50 in male, female, mice, rats (mg/kg): 3000, 2800, 2175, 2175 i.v.; >10000 all species orally; >5000 all species s.c. (Teelman) |
| MSDS Information | |
| Provider | Language |
| SigmaAldrich | English |
| Ceftriaxone sodium Usage And Synthesis | |
| Description | Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models. |
| Chemical Properties | White Crystalline Solid |
| Uses | antipsychotic |
| Uses | A potentially useful antibacterial agent for proteomics research. |
| Uses | An antibacterial, a third-generation cephalosporin. |
| Definition | ChEBI: Ceftriaxone disodium salt hemiheptahydrate is a cephalosporin. |
| Brand name | Rocephin (Roche). |
| Biological Activity | β -lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter. |
Products Application
As a third‑generation cephalosporin antibiotic, Ceftriaxone sodium eliminates pathogenic microorganisms through the inhibition of bacterial cell‑wall biosynthesis. Boasting a broad antibacterial profile and excellent chemical stability, this active pharmaceutical ingredient is indicated for the management of susceptible bacterial infections across multiple bodily systems, covering respiratory tract, urinary tract, intra‑abdominal and pelvic infections.
Company Profile
Shandong Furuida Chemical Co., Ltd. is a global start-up chemical foreign trade enterprise located in the core chemical industrial zone of Shandong Province. The company is distinguished by five core strengths that define its operations and value proposition.
First, the company owns and operates its own standardized factories, which provide independent production capacity and direct control over manufacturing processes. Second, the company has established an integrated operational framework that links production, quality control, cross-border trade, and global logistics into a single, efficient system. Third, the company’s product portfolio covers basic chemical raw materials, fine intermediates, chemical additives, and rubber and plastic feedstocks, serving industries including rubber and plastics, coatings, daily chemicals, building materials, and textiles.
Fourth, the company provides customized product solutions and one-stop foreign trade services that handle customs clearance, logistics coordination, and after-sales technical support on behalf of clients. Fifth, the company operates on a factory-direct supply model that offers transparent and stable pricing, supported by a full-process quality management system for consistent product quality and a mature logistics network for timely delivery.
The company serves chemical manufacturers, terminal processing plants, and cross-border traders across Asia, Europe, the Americas, and the Middle East. Its commitment to quality products, competitive pricing, and professional service forms the basis of long-term partnerships with clients worldwide.
