Products Description of 1,3-Dioxan-2-one CAS#2453-03-4
1,3-Dioxan-2-one (TMC) is a cyclic carbonate compound with the molecular formula C₄H₆O₃ and CAS number 2453-03-4. It is mainly used as a monomer in the synthesis of poly(trimethylene carbonate) (PTMC), a biodegradable polymer. This compound typically appears as white to off-white crystals and has a melting point of 45–47°C. It is readily soluble in organic solvents, including methanol. For proper storage and stability, it should be kept at a low temperature of 2–8°C under an inert gas atmosphere.

1,3-Dioxan-2-one Chemical Properties
| English Name | 1,3-Dioxan-2-one |
| English Synonyms | 1,3-Dioxan-2-one;1,3-Propylene carbonate;1,3-Propanediol cyclic carbonate;Carbonic acid 1,3-propanediyl ester;trimethylene carbonate1,3-Dioxan-2-one;1,3-Dioxan-2-one> Trimethylene carbonate (TMC) ,99%;TIA NFU-CHEM CAS NO.2453-03-4 1,3-Dioxan-2-one |
| CAS Number | 2453/3/4 |
| Molecular Formula | C4H603 |
| Molecular Weight | 102.09 |
| EINECS Number | 607-395-4 |
| Melting point | 45.0 to 49.0 °C |
| Boiling point | 135°C/4mmHg(lit.) |
| density | 1.200±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | soluble in Methanol |
| form | powder to crystal |
| color | White to Almost white |
| Risk Statements | 22-36 |
| Safety Statements | 24/25 |
| InChI | InChl=1S/C4H603/c5-4-6-2-1-3-7-4/h1-3H2 |
| InChIKey | YFHICDDUDORKJB-UHFFFAOYSA-N |
| SMILES | 01CCCOC1=0 |
Primary Applications
Ring-Opening Polymerization: 1,3-Dioxan-2-one is used in bulk ring-opening polymerization initiated by butyltin chlorides (BuSnCl, Bu₂SnCl, or Bu₃SnCl) to produce poly(trimethylene carbonate) (PTMC).
Copolymerization and Material Modification: It can be copolymerized with monomers such as ε-caprolactone or L-lactide to adjust the mechanical properties, degradation rate, and thermodynamic behavior of the resulting materials, making it promising for biomedical applications.
Homopolymer and Crosslinked Material Applications: PTMC can also be copolymerized with other lactone monomers. Following crosslinking, it can form a flexible, elastic network with properties similar to those of polydimethylsiloxane (PDMS) rubber.

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